GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study
نویسندگان
چکیده
منابع مشابه
GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study
BACKGROUND Chronic arsenic exposure is associated with an increased risk of skin, bladder and lung cancers. Generation of oxidative stress may contribute to arsenic carcinogenesis. METHODS To investigate the association between arsenic exposure and oxidative stress, urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) was evaluated in a cohort of 97 women recruited from an arsenic-endemic region of B...
متن کاملAuthor's response to reviews Title: GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study Authors:
1. The abstract has been corrected to address genotyping in the ‘methods’ section. 2. Abbreviated terms have been checked for consistency and fixed according to the reviewer’s suggestion. Methods 3. Per the reviewer’s suggestion, the first paragraph on page 7 was edited to clarify the number of samples collected from each participant. We collected three samples from each woman except one, who o...
متن کاملArsenic and Oxidative Stress in Pentylenetetrazole-induced Seizures in Mice
Background and Objective: Chronic arsenic toxicity is a widespread problem; the role of brain oxidative stress has been suggested in the genesis of epilepsy and in the post-seizure neuronal death. However, studies investigating the effects of arsenic on seizure and related mechanisms are limited. The purpose of this study was to examine the effect of prolonged exposure to sodium arsenite on oxi...
متن کاملDetermination of NRF2 and GSTM1 Expression and Biomarkers of Oxidative Stress on Smoking and Nonsmoking Sperm: A Pilot study
Background and Aims: Smoking has an influence on different semen parameters. It is regarded as a risk factor for infertility. This study aims to evaluate the effect of smoking cigarettes on the expression of nuclear factor erythroid 2-related factor 2 (NRF2) and glutathione S-transferase Mu 1 (GSTM1) genes and biomarkers of oxidative stress in sperm. Materials and Methods: A case-control study...
متن کاملBlack Carbon Exposure, Oxidative Stress Genes, and Blood Pressure in a Repeated-Measures Study
BACKGROUND Particulate matter (PM) air pollution has been associated with cardiovascular morbidity and mortality, and elevated blood pressure (BP) is a known risk factor for cardiovascular disease. A small number of studies have investigated the relationship between PM and BP and found mixed results. Evidence suggests that traffic-related air pollution contributes significantly to PM-related ca...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Health
سال: 2007
ISSN: 1476-069X
DOI: 10.1186/1476-069x-6-39